ZGF provided design services for Arizona State University (ASU) Biodesign Institute C, a five-story, 188,447 SF research facility with a basement level. Intended as a “workhorse” addition to existing research facilities on campus, Biodesign Institute C houses researchers from the Biodesign Institute, the Ira A. Fulton Schools of Engineering, and the College of Integrative Sciences and Arts. The building contains a mixture of laboratories, including high bay space, high hood-density laboratories, three levels of generic laboratories, as well as a Compact X-Ray Light Source facility in the basement. An extension of the existing Biodesign Institute, the building forms the northern edge of a research quadrangle centered on a James Turrell skyspace sculpture. Biodesign Institute C is targeting LEED Platinum®, with an energy savings goal of 44% compared to existing campus laboratories. The project team worked with the ASU Environmental Health and Safety Department to enact standards for reduced air change rates, which supported the use of a chilled beam hydronic system, where ventilation is decoupled from cooling. All non-laboratory air is transferred from perimeter offices through the laboratories, providing “free” air conditioning for the research spaces. Low-flow fume hoods minimize air change rates while lowering turbulence in laboratories, thereby increasing user safety. The high-performance double skin façade, consisting of an insulated metal panel and copper screen, minimizes heat gain, maximizes views, and increases daylight penetration into interior environments.